Reduced spike frequency adaptation in Purkinje cells of the vestibulocerebellum

Article ID	Journal	Published Year	Pages	File Type
6283689	Neuroscience Letters	2013	6 Pages	PDF

Abstract

âº Purkinje cells (PCs) show lobule-specific intrinsic excitability. âº Lobule X PCs possess lower degree of spike frequency adaptation (SFA). âº PCs in vestibulocerebellum exhibit higher firing regularity. âº SFA features of lobule X PCs are different according to firing frequency.

Keywords

DCN sAHP Vestibulocerebellum GFN FAHP HSN LFF HFF aCSF SFA TFn Slow afterhyperpolarization ISI PCs Spike frequency adaptation Purkinje cells Purkinje cell Coefficient of Variation interspike interval artificial cerebrospinal fluid Head-shaking nystagmus deep cerebellar nucleus Vestibular nucleus action potential fast afterhyperpolarization Patch clamp