| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6283834 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠Rat pMCAO model is used to analyze the neuroprotective effect of silibinin. ⺠Silibinin decreases neurological deficit, brain edema and infarct size. ⺠Silibinin up-regulates the expression of pAkt, pmTOR, HIF-1α and Bcl-2. ⺠Silibinin down-regulates the expression of Bax and NF-κB.
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Authors
Chaohui Wang, Zhihong Wang, Xiangjian Zhang, Xiaolin Zhang, Lipeng Dong, Yinxue Xing, Yanhua Li, Zongjie Liu, Linyu Chen, Huimin Qiao, Lina Wang, Chunhua Zhu,