| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6283855 | Neuroscience Letters | 2012 | 5 Pages |
Abstract
⺠Saikosaponin A dose-dependently reduced morphine self-administration. ⺠The effects of saikosaponin A were blocked by the GABA(B) receptor antagonist SCH 50911 but not the GABA(A) receptor antagonist bicuculline. ⺠Saikosaponin A did not affect food-reinforced responding. ⺠These results suggest that SSA may be effective in reducing the reinforcing effects of morphine.
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Authors
Seong Shoon Yoon, Hey Soo Kim, Hea-Young Cho, Jaesuk Yun, Eun Yong Chung, Choon-Gon Jang, Kwang Joong Kim, Chae Ha Yang,