Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6283935 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠Bv8 produces a direct and concentration-related release of CGRP. ⺠Bv8 pretreatment enhances Bv8- or capsaicin-stimulated CGRP release. ⺠Pretreatment with protein synthesis inhibitors blocks the late phase of Bv8-induced hyperalgesia. ⺠CGRP and SP are upregulated during the late phase of Bv8-induced hyperalgesia.
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Authors
Milena De Felice, Pietro Melchiorri, Michael H. Ossipov, Todd W. Vanderah, Frank Porreca, Lucia Negri,