Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284030 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠We examine the role of CRMP4 in MAG-induced axonal responses using CRMP4â/â mice. ⺠We show involvement of CRMP4 in MAG-induced inhibition of axonal outgrowth. ⺠MAG-induced axonal protection against acute toxic insult also requires CRMP4. ⺠CRMP4â/â DRG neurons have elevated sensitivity to Vincristine-induced axonal degeneration.
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Authors
Jun Nagai, Yoshio Goshima, Toshio Ohshima,