Association of mutations in the glucocerebrosidase gene with Parkinson disease in a Korean population

► Mutation of GBA, a causative gene for Gaucher disease is rare in Asia. ► We analyzed mutations in GBA in 277 Korean PD and 291 controls. ► Heterozygous mutation of GBA was found in 3.2% of PD cases and 0% in controls. ► Age-at-onset was younger in heterozygous GBA mutation carriers than non-carriers.