Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284060 | Neuroscience Letters | 2012 | 5 Pages |
Abstract
⺠Decreased high-frequency RRV (HF-RRV) in women with major depression (MDD). ⺠No differences between MDD and control women in heart rate or R-R intervals. ⺠Stress response circuitry hypoactivity related to lower HF-RRV in women with MDD. ⺠Gonadal hormones attenuated group differences in the HF-RRV effect on hypoactivity. ⺠Abnormal brain-heart coupling may have implications for MDD-CVD comorbidity.
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Authors
Laura M. Holsen, Jong-Hwan Lee, Sarah B. Spaeth, Lauren A. Ogden, Anne Klibanski, Susan Whitfield-Gabrieli, Richard P. Sloan, Jill M. Goldstein,