Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284069 | Neuroscience Letters | 2012 | 4 Pages |
Abstract
⺠Mas-related gene GPCR (Mrg) are uniquely expressed in dorsal root ganglia. ⺠Intrathecal Mrg agonist BAM8-22 does not change pain sensitivity. ⺠I.t. BAM8-22 decreased tail flick latency following treatment with pertussis toxin. ⺠BAM8-22 decreased pain sensitivity in the presence of U73122. ⺠The first study to show association of Mrg receptors with Gi/o and Gq proteins in vivo.
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Authors
Tingjun Chen, Dongmei Wang, Yanguo Hong,