| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284073 | Neuroscience Letters | 2012 | 5 Pages |
Abstract
⺠Basal ganglia circuits are a locus of primary pathology in major depression. ⺠Early age of onset is associated with greater circuit abnormality. ⺠Duration of illness does not impact circuit function. ⺠Disrupted basal ganglia-cortical connectivity may contribute to symptom expression.
Keywords
FDRWechsler Test of Adult ReadingWTARMADRSSCIDIFGMNIACCROIFunctional connectivityStriatumMajor depressionFunctional MRIfMRIfunctional magnetic resonance imagingSMAbasal gangliainferior frontal gyrusanterior cingulate cortexMontgomery–Åsberg Depression Rating Scaleregion-of-interestMontreal Neurological Institutefalse discovery rateSMA, supplementary motor areaCORE
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Authors
William R. Marchand, James N. Lee, Yana Suchy, Susanna Johnson, John Thatcher, Phillip Gale,