Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284102 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠Induced pluripotent stem cells (iPSCs) were generated from autistic patients. ⺠The iPSCs lines had traits similar to naturally occurring stem cells populations. ⺠Embryoid bodies with germ layer characteristics were derived from ASD-specific iPSC. ⺠Mature GABAergic neurons could be differentiated from the ASD-specific iPSC. ⺠iPSC provide valuable reagents for the characterization of the pathology of autism.
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Authors
Brooke A. DeRosa, Jessica M. Van Baaren, Gaurav K. Dubey, Joycelyn M. Lee, Michael L. Cuccaro, Jeffery M. Vance, Margaret A. Pericak-Vance, Derek M. Dykxhoorn,