Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284122 | Neuroscience Letters | 2012 | 5 Pages |
Abstract
⺠The proline-rich Akt substrate of 40 kDa (PRAS40) is a substrate of Akt. ⺠IGF-1 induces the phosphorylation of Akt at Thr473 and PRAS40 at Thr246 in PC12 cells. ⺠IGF-1 induced phosphorylation of PRAS40 is mediated by the PI3K/Akt pathway.
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Authors
Haitao Wang, Qishan Zhang, Lang Zhang, Peter J. Little, Xiaochun Xie, Qian Meng, Yannan Ren, Lihua Zhou, Guoquan Gao, Remi Quirion, Wenhua Zheng,