Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284154 | Neuroscience Letters | 2012 | 4 Pages |
Abstract
⺠8-OH-DPAT induces cognitive benefits after experimental TBI. ⺠5-HT1A receptor antagonism does not abate the 8-OH-DPAT-induced cognitive benefits. ⺠5-HT7 receptor antagonism attenuates the 8-OH-DPAT-induced cognitive benefits. ⺠The 8-OH-DPAT-induce cognitive benefits after TBI may be mediated more by 5-HT7 vs. 5-HT1A receptors. ⺠8-OH-DPAT-induced hypothermia is blocked by 5-HT1A, but not 5-HT7, receptor antagonism.
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Authors
Narayana K. Yelleswarapu, Justin K. Tay, William M. Fryer, Mansi A. Shah, Alexandra N. Garcia, Jeffrey P. Cheng, Anthony E. Kline,