Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284158 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠We screened drug compound library and identified Mefloquine, an anti-malarial drug as an autophagy inducer. ⺠Suppression of autophagy increased Mefloquine-mediated neurotoxicity. ⺠Thus, modulation of autophagy may help to efficiently regulate the neurological side effects of Mefloquine.
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Authors
Ji Hyun Shin, So Jung Park, Yoon Kyung Jo, Eun Sung Kim, Hee Kang, Ji-Ho Park, Eunjoo H. Lee, Dong-Hyung Cho,