Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284194 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠We synthesized a series of fisetin analogues lacking the 7-hydroxyl group. ⺠The 7-hydroxy group was not necessary for anti-amyloidogenic activity of flavonoids. ⺠3,3â²,4â²,5,5â²-Pentahydroxyflavone was the most potent inhibitor of Aβ fibrillization.
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Authors
Hiroko Ushikubo, Sayaka Watanabe, Yui Tanimoto, Kazuho Abe, Aiki Hiza, Takahiro Ogawa, Tomohiro Asakawa, Toshiyuki Kan, Tatsuhiro Akaishi,