The leucine-rich repeats of LINGO-1 are not required for self-interaction or interaction with the amyloid precursor protein

Article ID	Journal	Published Year	Pages	File Type
6284256	Neuroscience Letters	2012	4 Pages	PDF

Abstract

âº Interaction of cellular LINGO-1 with the amyloid precursor protein. âº The LRRs of LINGO-1 are not required for interaction with APP or self-interaction. âº Corroborates finding that LRRs are not required for inhibition of differentiation.

Keywords

MBP APP LRR EAE PDGFR NgR1 Nogo-66 receptor experimental autoimmune encephalomyelitis Leucine-rich repeats Leucine rich repeat self-interaction Immunoglobulin domain CNS central nervous system LINGO-1 Multiple sclerosis Myelin basic protein amyloid precursor protein platelet-derived growth factor receptor