Article ID Journal Published Year Pages File Type
6284265 Neuroscience Letters 2012 6 Pages PDF
Abstract
► Bolus injection of HS (3% NaCl) and 20% mannitol effectively dehydrates rat brain with edema. ► HS and mannitol injection activates microglia in healthy hemisphere in different degrees. ► HS compromises BBB more mildly than mannitol at the same time course. ► Bolus injection of HS and mannitol leads to cellular edema around the brain capillaries. ► Both HS and mannitol down-regulate AQP4 expression in the healthy brain without changing its distribution.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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