Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284265 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠Bolus injection of HS (3% NaCl) and 20% mannitol effectively dehydrates rat brain with edema. ⺠HS and mannitol injection activates microglia in healthy hemisphere in different degrees. ⺠HS compromises BBB more mildly than mannitol at the same time course. ⺠Bolus injection of HS and mannitol leads to cellular edema around the brain capillaries. ⺠Both HS and mannitol down-regulate AQP4 expression in the healthy brain without changing its distribution.
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Authors
Wei Jiang, Wan-Jun Cao, Yu-Kai Zhang, Xiao-Yan Wei, Fang Kuang,