| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284280 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠Caspase-3 activates and DNA fragmentation begins in endothelial cells and in neurons within 10 min after SAH. ⺠Only one third of cells positive for active caspease-3 undergo apoptosis. ⺠Necrosis (Fluoro-Jade B staining) begins 1 h after SAH. ⺠Apoptosis and necrotic cell death occurs concurrently in brain after SAH. ⺠These results emphasize the importance of early management to limit injury after SAH.
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Authors
Victor Friedrich, Rowena Flores, Fatima A. Sehba,