Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284334 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠The TDP-43 dysregulation in non-neuronal cells may contribute to the pathogenesis of ALS and FTLD. ⺠Overexpression of TDP-43 causes G2/M accumulation and death in non-neuronal cells. ⺠TDP-43-induced G2/M arrest is partly p53-dependent and death is p53-independent in HeLa cells.
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Neuroscience
Neuroscience (General)
Authors
Kikyo Lee, Hiroaki Suzuki, Sadakazu Aiso, Masaaki Matsuoka,