| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284347 | Neuroscience Letters | 2012 | 6 Pages |
Abstract
⺠We investigated if butamben inhibit sensory TRP channels, contributing to analgesia. ⺠Butamben inhibited TRPA1 and TRPV4 among sensory TRP channels in in vitro systems. ⺠In in vivo studies, butamben also attenuated TRPA1- and TRPV4-mediated nociception. ⺠In conclusion, inhibition of TRPA1 and TRPV4 contribute to butamben analgesia.
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Neuroscience (General)
Authors
Sangsu Bang, Tae-Jin Yang, Sungjae Yoo, Tae-Hwe Heo, Sun Wook Hwang,