Article ID Journal Published Year Pages File Type
6284382 Neuroscience Letters 2011 5 Pages PDF
Abstract
► We investigate the neuroprotective mechanism of hypothermia. ► Cerebral ischemia dissociates CaM-KIIα from nNOS in the CA1 hippocampus. ► Hypothermia induces the colocalization of CaM-KIIα with nNOS in CA1 hippocampus. ► CaM-KIIα attenuates the activity of nNOS. ► This effect is one of the neuroprotective mechanisms of hypothermia.
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Life Sciences Neuroscience Neuroscience (General)
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Hypothermia enhances the colocalization of calmodulin kinase IIα with neuronal nitric oxide synthase in the hippocampus following cerebral ischemia
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