Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284385 | Neuroscience Letters | 2011 | 6 Pages |
Abstract
⺠We examined the effect of five growth factors on miR-132 expression and synaptic protein levels. ⺠BDNF and bFGF upregulated levels of miR-132 in cortical cultures. ⺠BDNF, but not bFGF, increased expression of glutamate receptors. ⺠Only bFGF significantly upregulated miR-132 in cultured astroglial cells. ⺠Growth factor-induced miR-132 plays a different role in neurons and astrocytes.
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Authors
Tadahiro Numakawa, Noriko Yamamoto, Shuichi Chiba, Misty Richards, Yoshiko Ooshima, Soichiro Kishi, Kazuo Hashido, Naoki Adachi, Hiroshi Kunugi,