| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284459 | Neuroscience Letters | 2011 | 4 Pages |
Abstract
⺠100 PFU of Candid 1 strain of Junin virus induced 30% mortality in newborn mice. ⺠Candid 1 induced both acute and subacute/chronic murine central nervous system disease. ⺠Candid 1-induced CNS disease showed galectin-3 upregulation. ⺠Galectin-3 upregulation correlated with significant glia activation and viral burden. ⺠Galectin-3 may play an important role in viral-induced CNS disease.
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Authors
Carolina Jaquenod De Giusti, Lucrecia Alberdi, Jesica Frik, MarÃa F. Ferrer, Emilia Scharrig, Mirta Schattner, Ricardo M. Gomez,