Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284489 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠PDE3B pathway plays an important role in mediating hypothalamic action of leptin. ⺠This study shows expression of PDE3B in POMC and NPY neurons in the hypothalamus. ⺠PDE3B is also expressed in the hypothalamic nuclei implicated in energy homeostasis. ⺠Direct PDE3B signaling appears to mediate leptin action in POMC and NPY neurons.
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Authors
Maitrayee Sahu, David G. Litvin, Abhiram Sahu,