| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284512 | Neuroscience Letters | 2011 | 4 Pages |
Abstract
⺠Previously we showed that CGRP can increase ectopic discharge at nerve injury sites. ⺠Here we monitor the effect of anti-CGRP antibody on injured nerve fibre activity. ⺠Systemic anti-CGRP does not modify activity in injured lingual nerve fibres. ⺠Activity in injured lingual nerve fibres is not affected by sequestration of CGRP. ⺠Other modulators may offer better therapeutic targets for nerve injury-induced pain.
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Neuroscience
Neuroscience (General)
Authors
Katie E. Bowler, Matthew A. Worsley, Lisa Broad, Emmanuel Sher, Robert Benschop, Kirk Johnson, Fiona M. Boissonade, Peter P. Robinson, Julian M. Yates,