Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284585 | Neuroscience Letters | 2012 | 5 Pages |
Abstract
⺠Some cocaine effects are related to angiotensin II in the brain. ⺠The main angiotensin II generating enzyme in the brain is angiotensin I-converting enzyme (ACE). ⺠Acute and subchronic cocaine increases ACE mRNA and activity in striatum and frontal cortex. ⺠Our results suggest the involvement of brain ACE in the Ang II related effects of cocaine administration.
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Authors
Bruna Visniauskas, Juliana C. Perry, Vitor Oliveira, Fernanda M. Dalio, Monica L. Andersen, Sergio Tufik, Jair R. Chagas,