| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284597 | Neuroscience Letters | 2012 | 5 Pages |
Abstract
⺠Binding pocket for the OX1 orexin receptor-selective antagonist, SB-334867, investigated. ⺠Construction of chimaeric OX1-OX2 orexin receptors. ⺠Evaluation of SB-334867's affinity (KB) from inhibition of responses to orexin-A. ⺠SB-334867's affinity mostly controlled by the area between transmembrane helices 2 and 4.
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Authors
Jaana Putula, Jyrki P. Kukkonen,