Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284696 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠miRNA-146a is a brain-enriched miRNA involved in inflammation in multiple human brain cell types. ⺠miRNA-146a is up-regulated in human brain cells stressed with Aβ42 peptides + TNFα. ⺠Up-regulated miRNA-146a was found to be associated with down-regulation of CFH, IRAK-1, and TSPAN12. ⺠Different brain cell types each respond differently to Aβ42 + TNFα-triggered stress.
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Authors
Yuan Yuan Li, Jian Guo Cui, Prerna Dua, Aileen I. Pogue, Surjyadipta Bhattacharjee, Walter J. Lukiw,