Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284752 | Neuroscience Letters | 2011 | 4 Pages |
Abstract
⺠Neonatal hypoxia caused increased total 5-HT and 5-HT2A receptor expression in corpus striatum. ⺠The expression of transcription factor HIF1 was up regulated in hypoxic condition. ⺠Glucose resuscitation, alone and with oxygen, reversed the serotonergic and HIF1 alterations. ⺠Common clinical practice of 100% oxygen or epinephrine upset the serotonergic system. ⺠This highlights the importance of glucose supplementation in neonatal care to hypoxia.
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Authors
T.R. Anju, C.S. Paulose,