Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284772 | Neuroscience Letters | 2011 | 6 Pages |
Abstract
⺠Human iPSCs provide an avenue for investigating neurological disease mechanisms. ⺠Many neurodegenerative diseases are commonly misdiagnosed in live patients. ⺠Postmortem histopathological review of a donor brain increases diagnostic accuracy. ⺠Postmortem cells can be made into iPSCs that are capable of neural differentiation. ⺠Postmortem fibroblast proliferation is effected by biopsy site but not donor age.
Keywords
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Brooke E. Hjelm, Jon B. Rosenberg, Szabolcs Szelinger, Lucia I. Sue, Thomas G. Beach, Matthew J. Huentelman, David W. Craig,