Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284796 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠A novel transgenic C/EBP-luc (luciferase) reporter mouse model is described. ⺠C/EBP activity induced by systemic inflammation is monitored in real-time. ⺠A striking brain response to inflammation is detected in vivo by C/EBP-luc mice. ⺠The effect of dexamethasone on brain inflammation is assayed noninvasively. ⺠The C/EBP-luc model is a potential tool for in vivo studies on neuroinflammation.
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Authors
Luis Lopez de Heredia, Archana Gengatharan, Julie Foster, Stephen Mather, Charalambos Magoulas,