Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6284866 | Neuroscience Letters | 2011 | 5 Pages |
Abstract
⺠We examined the effects of PREP inhibition on rat brain peptide levels. ⺠For the first time in PREP studies, peptides were measured in brain microdialysates. ⺠Brain PREP was inhibited with KYP-2047 (50 μmol/kg i.p.). ⺠No changes in extracellular neurotensin or substance P levels were detected. ⺠PREP does not regulate the extracellular levels of neurotensin or substance P.
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Authors
Aaro J. Jalkanen, Katja Savolainen, Markus M. Forsberg,