| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6284967 | Neuroscience Letters | 2011 | 6 Pages |
Abstract
⺠Paroxetine, but not placebo, treatment is associated with increased OFC activation. ⺠Paroxetine and placebo treatments are both associated with increased activation in the ACC. ⺠SSRI treatment may act more specifically on orbitofrontal circuits that modulate fear extinction. ⺠These pilot data reveal putative mechanisms for SSRI treatment in PTSD. ⺠Our findings substantiate the need for further imaging studies of SSRI treatment in PTSD.
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Authors
Negar Fani, Ali Ashraf, Nadeem Afzal, Farhan Jawed, Noriyuki Kitayama, Lai Reed, J. Douglas Bremner,