In vitro effect of altering potassium concentration in artificial endolymph on apoptosis and ultrastructure features of olfactory bulb neural precursor cells

▶ Manipulating K+ in EL may be a new avenue to promote transplanted cells survival. ▶ Altering potassium concentration in artificial endolymph cultured NPCs 24 h. ▶ Observe the cell of survival, apoptotic and ultrastructure features changes. ▶ High K+ concentration 50 mM or more let NPCs a series of apoptotic events. ▶ Lower K+ concentration improved the survival rate of cultured NPCs.