Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6286134 | Neuroscience Research | 2015 | 8 Pages |
Abstract
In the current literature, we review our published results showing increased alert behaviors by constant light, and then, attempted to extend our additional analysis to seek age-dependent susceptibility to constant light. We then present the neurobiological mechanisms with reference to previous research reports. The current review suggests possible existence of a susceptible period earlier than three to five month-old in the environment-induced developmental disorder model, supposedly like attention deficit hyperactive disorders (ADHD) or oppositional defiant disorder (ODD).
Keywords
sPVZVLPOipRGCDTALHbGSHSCNNOSDATPCAmedial amygdalaAChEOppositional Defiant Disorderautistic spectrum disordersacetylcholine esteraseDehydroascorbic acidDopamine transporterADHDPrincipal component analysisMultivariate analysisconstant darklateral habenulaDIACircadian rhythmSERTserotonin transporterintrinsically photosensitive retinal ganglion cellsODDventrolateral preoptic areaASDconstant lightnitric oxide synthaseSuprachiasmatic nucleiChATcholine acetyltransferaseGlutathione
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Authors
Mamiko Koshiba, Aya Senoo, Genta Karino, Simpei Ozawa, Ikuko Tanaka, Yoshiko Honda, Setsuo Usui, Tohru Kodama, Koki Mimura, Shun Nakamura, Tetsuya Kunikata, Hideo Yamanouchi, Hironobu Tokuno,