| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6286336 | Neuroscience Research | 2014 | 5 Pages |
Abstract
We investigated ascending somatosensory pathways in neonatally hemidecorticated rats. Injection of an anterograde tracer, biotinylated dextran amine (BDA), into the contralesional dorsal root ganglions revealed ipsilateral projections to the dorsal column nuclei (DCN) in hemidecorticated rats as well as in normal rats. Injection of BDA into the DCN on the same side revealed that while most axons projected to the contralateral thalamus, some axons were detected in the ipsilateral thalamus in hemidecorticated rats while such projections were rarely detected in normal rats. The results suggest that aberrant ipsilateral projections of DCN neurons contralateral to the lesion developed after the hemidecortication.
Related Topics
Life Sciences
Neuroscience
Neuroscience (General)
Authors
Oraphan Wanakhachornkrai, Tatsuya Umeda, Kaoru Isa, Mayuree H. Tantisira, Boonyong Tantisira, Tadashi Isa,