Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6286438 | Neuroscience Research | 2011 | 8 Pages |
Abstract
â¶ Some atypical antipsychotic drugs have protective effects against oxidative stress. â¶ We observe antioxidant effect using MPP+ toxicity model causing oxidative stress. â¶ Olanzapine, aripiprazole and ziprasidone modulate the levels of ROS, SOD and Bax. â¶ However, haloperidol fails to show antioxidant effects. â¶ These atypical antipsychotic drugs have antioxidant effects with clinical relevance.
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Authors
Sung Woo Park, Chan Hong Lee, Jung Goo Lee, Luck Woo Kim, Bae Sub Shin, Bong Ju Lee, Young Hoon Kim,