Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6286533 | Progress in Neurobiology | 2014 | 10 Pages |
Abstract
This review focuses on reported reprogramming techniques and innovative techniques that can be further explored in this area, as well as on the criteria for the phenotypic characterization of iNSCs and their use in developing novel therapeutic strategies for neurological diseases.
Keywords
EGFPTDs(E)GFPLIFTuj1Induced neural stem cellsESCsPLPSox2MAP2NSCsbHLHIPSCsMEFsDcxFGFmiRNAsmRNAGFAP(enhanced) green fluorescent proteinCPPsmessenger RNAbasic helix–loop–helixReprogrammingBrdUbromodeoxyuridinetyrosine-hydroxylaseSelf-renewalProtein transduction domainsCNSdoublecortinmicroRNAsiMNInduced pluripotent stem cellsInduced neuronal cellsEmbryonic stem cellsNeural stem cellscentral nervous systemepidermal growth factorleukemia inhibitory factorfibroblast growth factormouse embryonic fibroblastsGlial fibrillary acidic proteinmicrotubule-associated protein 2cell-penetrating peptidesMultipotencyClinical application
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Neuroscience
Neuroscience (General)
Authors
Margherita Ruggieri, Giulietta Riboldi, Simona Brajkovic, Monica Bucchia, Nereo Bresolin, Giacomo P. Comi, Stefania Corti,