| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6286610 | Progress in Neurobiology | 2011 | 27 Pages |
Abstract
ⶠBridging large nerve gaps with grafts is necessary for peripheral nerve regeneration. ⶠTissue engineered nerve grafts are constructed by combining neural scaffold with support cells and/or growth factors. ⶠWe describe basic components of tissue engineered nerve grafts in terms of structure, feature and functions. ⶠWe discuss current clinical applications and future perspectives of tissue engineered nerve grafts.
Keywords
FK506CNTFNGFGDNFECMNT-3PDGFNT-4/5PLLAPSUPLCPPEePTFESTXFGFslacZPHBHHxLIFNGCPPyPGAPCLMSCsIGFGFPPLGAPolypyrrolePLABDNFCSAPeripheral nerve regenerationβ-galactosidaseBrdUbromodeoxyuridineTacrolimusTrkESCCNSRetinoic acidEmbryonic stem cellMesenchymal stem cellscentral nervous systemperipheral nervous systemcyclosporin ANerve gapleukemia inhibitory factorFibroblast Growth FactorsGrowth factorsVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factornerve growth factorInsulin-like growth factorBrain-derived neurotrophic factorciliary neurotrophic factorExtracellular matrixneurotrophin-4/5neurotrophin-3Green fluorescence proteinPoly(3-hydroxybutyrate-co-3-hydroxyhexanoate)Poly(L-lactic acid)poly(glycolic acid)expanded polytetrafluoroethylenePolysulfonePolyphosphoesterPolycaprolactonePNSNerve guidance conduitTyrosine kinase receptor
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Authors
Xiaosong Gu, Fei Ding, Yumin Yang, Jie Liu,