| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6287151 | Hearing Research | 2016 | 14 Pages |
Abstract
Distortion product otoacoustic emissions (DPOAEs) were used to assess outer hair cell (OHC) integrity in human ears with age-related hearing loss. Sound pressure measurements were made in the ear canal over the stimulus range 40-90Â dB SPL (L2), with L1Â =Â 0.45*L2Â +Â 44 with F2Â =Â 2 and 3 or 4Â kHz. Model-generated DPOAE I/O functions were fit to DPOAE data to quantify the contribution of loss of nonlinearity (OHC loss) to the hearing loss. Results suggest OHC loss as a contributing cause of age-related hearing, regardless of audiogram configuration. It seems likely that OHC and strial pathology co-exist in ears with AHL.
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Authors
Margarete A. Ueberfuhr, Hannah Fehlberg, Shawn S. Goodman, Robert H. Withnell,