| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6287572 | Hearing Research | 2013 | 11 Pages |
Abstract
⺠d-met and ALCAR were administered by four systemic routes IV, IT, OG, & IN. ⺠Levels in cochlear tissues and fluids were measured by 14C counts and LC/MS. ⺠IT delivery resulted in the highest relative concentration of methionine & ALCAR. ⺠d-met IT administration increased both methionine & ALCAR levels in cochlear fluids. ⺠Antioxidants administered by IT could be a therapeutic tool for hearing protection.
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Authors
Yohann Grondin, Douglas A. Cotanche, Otto Manneberg, Ramon Molina, J. Humberto Treviño-Villarreal, Rosalinda Sepulveda, Royce Clifford, Magda E. Bortoni, Scott Forsberg, Brian LaBrecque, Larisa Altshul, Joseph D. Brain, Ronald L. Jackson,