Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6287581 | Hearing Research | 2013 | 12 Pages |
Abstract
⺠We established a rat marginal cells (MCs) senescence model with common deletion. ⺠PGC-1α and its downstream factors expressed in MCs. âºÂ Nuclear-mitochondrial interaction played an important role in presbycusis. ⺠PGC-1α overexpression could protect MCs with common deletion from cellular senescence.
Keywords
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Sensory Systems
Authors
Xue-Yan Zhao, Jin-Li Sun, Yu-Juan Hu, Yang Yang, Wen-Juan Zhang, Yuan Hu, Jun Li, Yu Sun, Yi Zhong, Wei Peng, Hong-Lian Zhang, Wei-Jia Kong,