Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6290657 | Experimental Parasitology | 2015 | 7 Pages |
Abstract
- Natural products were screened against L.âmexicana cathepsin L (rCPB2.8).
- A triterpene and some flavonoids are inhibitors of rCPB2.8.
- The inhibitors of rCPB2.8 are partially noncompetitive and uncompetitive.
- The mechanism would be an advantage in the search for selective inhibitors.
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Authors
Lorena R.F. de Sousa, Hongmei Wu, Liliane Nebo, João B. Fernandes, Maria F. das G.F. da Silva, Werner Kiefer, Tanja Schirmeister, Paulo C. Vieira,