| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6291196 | Experimental Parasitology | 2013 | 8 Pages |
Abstract
- Chemotaxis plays a role in Leishmania differentiation and in parasite-host-cell interaction.
- The two-chamber capillary assay evaluates MTX-conjugates chemotactic properties in Leishmania.
- The N-terminal amino acid (Ser or Glu) in the branches affect MTX-conjugates chemotactic activity.
- Attachment sites in MTX-conjugates (α- or γ-groups) determine their chemotactic activity.
- Cytotoxic and cytostatic effects suggest that MTX-conjugates are selective for Leishmania.
Keywords
Related Topics
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Immunology and Microbiology
Parasitology
Authors
Emilia DÃaz, László Köhidai, Arturo RÃos, Oriana Vanegas, Adrian Silva, Rita Szabó, Gábor MezÅ, Ferenc Hudecz, Alicia Ponte-Sucre,