| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6291418 | Experimental Parasitology | 2012 | 7 Pages |
Abstract
⺠Emodepside is a broad spectrum cyclooctadepsipeptide anthelmintic drug. ⺠It has a mode of action different from the other classical groups of anthelmintics. ⺠We review its mode of action that show it inhibits neuronal and muscle activity. ⺠Rescue experiments suggest emodepside opens nematode Ca-dependent SLO-1 K channels. ⺠Its slow time-dependent action suggests it does not act in the extracellular domain of these channel.
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Authors
R.J. Martin, S.K. Buxton, C. Neveu, C.L. Charvet, A.P. Robertson,