Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6291496 | Experimental Parasitology | 2012 | 7 Pages |
Abstract
⺠Thiadiazole analogs induced loss of plasma membrane integrity, DNA breakage and proteolysis of PARP. ⺠These analogs were shown to induce necrosis on Leishmania major promastigotes. ⺠These analogs decreased acid phosphatase activity significantly during virulent growth stage of promastigotes.
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Authors
Sussan K. Ardestani, Fatemeh Poorrajab, Sepideh Razmi, Alireza Foroumadi, Soheila Ajdary, Behnaz Gharegozlou, Mina Behrouzi-Fardmoghadam, Abbas Shafiee,