Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6291524 | Experimental Parasitology | 2012 | 6 Pages |
Abstract
⺠Piplartine is able to kill Schistosoma mansoni schistosomula of different ages. ⺠The lethal effect occurred in a dose-dependent manner and was also dependent on the age of the parasite. ⺠Confocal microscopy observation revealed that piplartine induced morphological changes on the tegument of the worms. ⺠Piplartine is a promising compound that could be used for the development of new schistosomicidal agent.
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Authors
Josué de Moraes, Carlos Nascimento, Lydia F. Yamaguchi, Massuo J. Kato, Eliana Nakano,