Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6291807 | Experimental Parasitology | 2012 | 7 Pages |
Abstract
⺠Examined effects of acetyl-CoA carboxylase inhibitor haloxyfop on Trypanosoma brucei. ⺠Haloxyfop inhibited T. brucei acetyl-CoA carboxylase activity in vitro. ⺠Haloxyfop inhibited the growth of T. brucei in culture. ⺠Haloxyfop did not affect fatty acid elongation of T. brucei in culture. ⺠Haloxyfop likely has off-target effects on T. brucei.
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Authors
Patrick A. Vigueira, Kimberly S. Paul,