| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6291835 | Experimental Parasitology | 2012 | 9 Pages |
Abstract
⺠Trypanosoma brucei encodes a homolog of Escherichia coli AlkB, which repairs alkylation damage of DNA. ⺠TbABH belongs to the Fe(II) and alpha-ketoglutarate dioxygenase superfamily. ⺠TbABH binds DNA, with a preference for alkylated DNA. ⺠TbABH complements an E. coli alkB knockout.
Keywords
Related Topics
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Immunology and Microbiology
Parasitology
Authors
Jana M. Simmons, Donna J. Koslowsky, Robert P. Hausinger,