Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6291924 | Experimental Parasitology | 2011 | 7 Pages |
Abstract
⺠Synthesis of endochin analogs with enhanced antiparasitic activity. ⺠Identification of endochin analogs that are equipotent against multidrug-resistant parasites. ⺠Identification of endochin analogs that are equipotent against atovaquone resistant parasites. ⺠Prodrug of endochin analog ELQ-121 cures murine malaria by oral route.
Keywords
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Immunology and Microbiology
Parasitology
Authors
Rolf Winter, Jane X. Kelly, Martin J. Smilkstein, David Hinrichs, Dennis R. Koop, Michael K. Riscoe,