Article ID Journal Published Year Pages File Type
6291991 Experimental Parasitology 2012 10 Pages PDF
Abstract
► We generated two panels of epitope-matched mouse IgGs anti-PfMSP119 and PyMSP119. ► All IgGs were confirmed to be of the correct subclass and bound to the antigens. ► IgG1 triggers PfMSP119-specific NADPH oxidase activation through FcγR cross-linking. ► Passive transfer of IgG1 anti-PfMSP119 did not protect mice from infection.
Related Topics
Life Sciences Immunology and Microbiology Parasitology
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